Effects of aerobic exercise on respiratory and cardiovascular function and associated barriers in Parkinson’s disease: a narrative review of randomized controlled trials

Jinjuta, Suwannarat and Kanjana, Niemrungruang and Richard, Webb and Watesinee, Kaewkhuntee and Amporn, Nuntapornsak and Fuengfa, Khobkhun (2026) Effects of aerobic exercise on respiratory and cardiovascular function and associated barriers in Parkinson’s disease: a narrative review of randomized controlled trials. Physical Therapy Reviews. ISSN 1083-3196

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Abstract

Parkinson’s disease (PD) patients benefit from aerobic exercise, but cardiovascular impairments may limit participation and outcomes. This review aims to investigate the effect of aerobic exercise on respiratory function, cardiopulmonary fitness, autonomic cardiovascular function and functional capacity in individuals with PD. A narrative review of randomized controlled trials (RCTs) was conducted using PubMed, PEDro, and Scopus databases. Studies examining cardiovascular responses to aerobic exercise in PD were included and five RCTs were analyzed. Aerobic exercise improved respiratory pressures and some markers of cardiovascular function, but limitations remained. Cardiovascular barriers included autonomic dysfunction, reduced cardiopulmonary fitness, and respiratory muscle weakness. Aerobic exercise can produce beneficial effects on respiratory muscle strength, and blood pressure regulation in individuals with PD. However, persistent cardiovascular impairments, including autonomic dysfunction and limited cardiopulmonary fitness, continue to restrict full exercise benefits. Tailored interventions and comprehensive assessments are necessary to maximize safety and therapeutic benefits.

Item Type:	Article
Faculty / Department:	Faculty of Human and Digital Sciences > School of Health and Sport Sciences
Depositing User:	Richard Webb
Date Deposited:	09 Feb 2026 11:44
Last Modified:	09 Feb 2026 11:44
URI:	https://hira.hope.ac.uk/id/eprint/4845

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