Afiqah, Wajihah S and Sankar, D S and Nagar, Atulya K. (2023) Influence of thrombosis, stenosis and catheter on rheological characteristics of blood: A systematic review. Archive of Applied Mechanics, 93. ISSN 0939-1533 (Accepted for Publication)
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Abstract
Understanding potential disease causation due to stenosis and thrombosis and its treatment by utilising catheters and magnetic field has gained increasing attention from experts worldwide. Endothelial injury or plaque rupture can trigger thrombosis, which can cut off the supply of blood to the heart or brain, causing stroke or a myocardial infarction. In the regions of stenosis, narrowing of lumen of arteries and high shear rate generate conditions that increase platelet build-up and blockage. Treatment like catheters and magnetic field are famously being implemented in modern medicine as a way of removing blood clots inside a constricted artery in light to improve the blood circulation inside a human body. This article reviews the impact of the simultaneous presence of stenosis and thrombosis on blood flow characteristics and the effects of using catheter in clearing the obstructions in the lumen of blood vessels. We also introduce significant recent development on blood flow modelling relating to the subject matter. A sample mathematical model is considered from the literature to explain the influence of aforesaid arterial constrictions and clinical therapy for future directions in the medical field. Based on the collected literature, we note that the angioplasty catheter greatly increases blood flow as compared to infusion and guidewire catheters because it uses a balloon-tipped catheter to remove occlusions in the artery lumen. This comprehensive review and the proposed mathematical model together with the clinical data may offer directions for further studies, especially on one specific type of catheter for balloon angioplasty as the best treatment for clearing the occlusions in the diseased artery.
| Item Type: | Article |
|---|---|
| Additional Information and Comments: | This is the authors' version of an article that has been accepted for publication in the Archive of Applied Mathematics. The final, published version is available from: https://link.springer.com/article/10.1007/s00419-023-02496-z |
| Keywords: | Blood flow; Constrictions in arteries; Catheters; Thrombosis; Non-Newtonian fluids; Clinical applications |
| Faculty / Department: | Faculty of Human and Digital Sciences > School of Computer Science and the Environment |
| Depositing User: | Atulya Nagar |
| Date Deposited: | 02 Oct 2023 13:42 |
| Last Modified: | 14 Jan 2025 16:29 |
| URI: | https://hira.hope.ac.uk/id/eprint/4036 |
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