Impact of supine versus upright exercise on muscle deoxygenation heterogeneity during ramp incremental cycling is site specific

Goulding, Richie P and Okushima, Dai and fukuoka, Yoshiyuki and Marwood, Simon and Kondo, Narihiko and Poole, David and Barstow, Thomas and Koga, Shunsaku (2021) Impact of supine versus upright exercise on muscle deoxygenation heterogeneity during ramp incremental cycling is site specific. European Journal of Applied Physiology, 121 (5). pp. 1283-1296. ISSN 1439-6319

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Abstract

Purpose: We tested the hypothesis that incremental ramp cycling exercise performed in the supine position (S) would be associated with an increased reliance on muscle deoxygenation (deoxy[heme]) in the deep and superficial vastus lateralis (VLd and VLs, respectively) and the superficial rectus femoris (RFs) when compared to the upright position (U). Methods: 11 healthy men completed ramp incremental exercise tests in S and U. Pulmonary V ̇O2 was measured breath-by-breath; deoxy[heme] was determined via time-resolved-NIRS in the VLd, VLs and RFs. Results: Supine exercise increased the overall change in deoxy[heme] from baseline to maximal exercise in the VLs (S: 38 ± 23 vs. U: 26 ± 15 μM, P < 0.001) and RFs (S: 36 ± 21 vs. U: 25 ± 15 μM, P < 0.001), but not in the VLd (S: 32 ± 23 vs. U: 29 ± 26 μM, P > 0.05). Conclusions: The present study supports that the impaired balance between O2 delivery and O2 utilization observed during supine exercise is a regional phenomenon within superficial muscles. Thus, deep muscle defended its O2 delivery/utilization balance against the supine-induced reductions in perfusion pressure. The differential responses of these muscle regions may be explained by a regional heterogeneity of vascular and metabolic control properties, perhaps related to fiber type composition.

Item Type:	Article
Additional Information and Comments:	The final, published version is available open access from: https://link.springer.com/article/10.1007/s00421-021-04607-6 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
Keywords:	near-infrared spectroscopy, oxygen delivery, oxygen utilization, exercise tolerance, muscle activation
Faculty / Department:	Faculty of Human and Digital Sciences > School of Health and Sport Sciences
Depositing User:	Simon Marwood
Date Deposited:	25 May 2021 13:21
Last Modified:	23 May 2022 10:40
URI:	https://hira.hope.ac.uk/id/eprint/3291

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