Original Research Skin Microvascular Reactivity in Children and Adolescents With Type 1 Diabetes in Relation to Levels of Physical Activity and Aerobic Fitness

Roche, Denise and Edmunds, Sarah and Cable, Tim and Didi, Mo and Stratton, Gareth (2008) Original Research Skin Microvascular Reactivity in Children and Adolescents With Type 1 Diabetes in Relation to Levels of Physical Activity and Aerobic Fitness. Paediatric Exercise Science, 20 (4). pp. 426-438. ISSN 0899-8493

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Abstract

No studies to date have evaluated the relationship between exercise and microvascular function in youth with type 1 diabetes mellitus (T1DM). Twenty-nine complication free children and adolescents with T1DM were assessed for skin microvascular reactivity, aerobic fitness (VO2peak) and physical activity. VO2peak but not physical activity was significantly and independently associated with maximal hyperemia of the skin microcirculation (p < .01). No significant associations were found between venoarteriolar reflex (VAR) vasoconstriction and VO2peak or physical activity. Aerobic fitness may be an important indicator or mediator of effective microvascular endothelial function in youth with T1DM.

Item Type: Article
Subjects: Q Science > QP Physiology
Faculty / Department: Faculty of Human and Digital Sciences > School of Health and Sport Sciences
Depositing User: Susan Murray
Date Deposited: 05 Mar 2014 12:33
Last Modified: 05 Mar 2014 12:33
URI: https://hira.hope.ac.uk/id/eprint/304

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