Stockton, Angela and Farhat, Grace and McDougall, Gordon and Al-Dujaili, Emad (2017) Effect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomised clinical trial. Journal of Nutritional science, 6 (e39). ISSN 2048-6790
Preview |
Text
published paper.pdf - Published Version Available under License Creative Commons Attribution. Download (336kB) | Preview |
Abstract
Pomegranate (Punica granatum), a polyphenol-rich fruit, has been suggested to reduce cardiovascular risk due to its antioxidant properties. Hypertension and
obesity are the most preventable cardiovascular risk factors. Few studies on blood pressure and/or body-weight status have been conducted in human subjects. Previous investigations have tended to focus on pomegranate juice. The aim of the present study was to investigate the effect of pomegranate extract (PE) on blood pressure and anthropometric measures in adults with no symptomatic disease. A total of fifty-five participants enrolled in a randomised double-blinded placebo-controlled clinical trial where they were assigned to either PE capsules or placebo capsules for 8 weeks. Blood pressure, body
weight, waist circumference, waist:hip ratio (WHR) and body composition (lean body mass, body fat) were measured at baseline, week 4 and week 8. Results showed a significant decrease in diastolic blood pressure after 8 weeks (by 2·79 (SD 5·32) mmHg; P < 0·05), while the decrease in systolic blood pressure did not reach statistical significance (2·57 (SD 7·4) mmHg; P > 0·05). Body fat percentage, lean body mass, waist circumference and WHR did not significantly differ between groups at the end of the intervention. Results suggest that PE may reduce blood pressure and possibly prevent hypertension in the normotensive population. Further large trials are required to elucidate this effect.
| Item Type: | Article |
|---|---|
| Additional Information and Comments: | Stockton, A., Farhat, G., McDougall, G., & Al-Dujaili, E. (2017). Effect of pomegranate extract on blood pressure and anthropometry in adults: A double-blind placebo-controlled randomised clinical trial. Journal of Nutritional Science, 6. doi:10.1017/jns.2017.36 Copyright held by Cambridge University Press. Available under Open Access. |
| Faculty / Department: | Faculty of Human and Digital Sciences > School of Health and Sport Sciences |
| Depositing User: | Grace Farhat |
| Date Deposited: | 14 Dec 2017 16:31 |
| Last Modified: | 14 Dec 2017 16:31 |
| URI: | https://hira.hope.ac.uk/id/eprint/2316 |
Actions (login required)
 |
View Item |
Altmetric
Altmetric
