Effects of Stevia extract on postprandial glucose 3 response, satiety and Energy intake: A three-arm 4 crossover trial.

Farhat, Grace and Berset, Victoria and Moore, Lauren (2019) Effects of Stevia extract on postprandial glucose 3 response, satiety and Energy intake: A three-arm 4 crossover trial. Nutrients, 11 (12). ISSN 2072-6643

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Abstract

Non-nutritive sweeteners (NNS) are suggested to lower Energy intake in the diet, but they
11 have been paradoxically involved in the epidemic of obesity and Type 2 diabetes. Stevia is the least
12 studied sweetener. This study aims to investigate the effect of stevia on postprandial glucose levels,
13 appetite and food intake. Methods: Thirty participants (20 females/10 males; 26.1 (10.56) years; BMI
23.44 (3.42) Kg/m2 14 ) took part in a three-arm crossover trial where they received preloads of water,
15 sugar (60g) and stevia (1g) on 3 different days, followed by an ad-libitum pizza lunch. Breakfast was
16 standardized. A one-day diet diary was collected on each test day. Visual analogue scales (VAS)
17 were used to assess subjective feelings of appetite. Blood glucose samples were collected at 30-
18 minute intervals until 120-min post lunch. Results: Energy intake did not significantly differ
19 between preloads for ad libitum meal (p=0.78) and overall day (p=0.33). VAS scores for hunger and
20 desire to eat (DTE) were lower following stevia preload compared to water (p<0.05). After adjusting
21 for the sugar preload Calorie content, postprandial glucose levels did not significantly differ
22 between interventions. Conclusion: Stevia lowers appetite sensation and does not further increase
23 food intake and postprandial glucose levels. It could be a useful strategy in obesity and diabetes
24 prevention and management.

Item Type: Article
Additional Information and Comments: © 2019 by the authors. Submitted for possible open access publication under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Non-nutritive sweeteners; stevia; glucose; appetite; food intake; diabetes; obesity
Faculty / Department: Faculty of Science > School of Health Sciences
Depositing User: Grace Farhat
Date Deposited: 12 Dec 2019 10:10
Last Modified: 14 Feb 2020 13:21
URI: https://hira.hope.ac.uk/id/eprint/2984

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