Flow simulation in coronary artery models: An investigation of the effect of variable angulations at the left coronary artery

Chaichana, Thanapong and Sun, Zhonghua and Tungjitkusolmun, Supan and Sangworasil, Manas (2010) Flow simulation in coronary artery models: An investigation of the effect of variable angulations at the left coronary artery. In: 2010 IEEE 23rd International Symposium on Computer-Based Medical Systems (CBMS). IEEE eXpress Conference Publishing, Perth, pp. 279-284. ISBN 9781424491674

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Official URL: http://ieeexplore.ieee.org/document/6042656/

Abstract

This study was designed to investigate the hemodynamics in the left coronary artery with the aim of identifying the relationship between angulations of left coronary bifurcation and development of atherosclerosis. Six 3D left coronary models were simulated for computational fluid dynamic analysis. The left coronary model was composed of left main stem, left anterior descending and left circumflex branches. The angulations at the left bifurcation were simulated with angles ranging from 90°, 75°, 60°, 45°, 30° to 15°. The computational fluid dynamic was used for analysis of flow velocity, wall pressure and wall shear stress. Our results showed that apparent low shear stress and high wall pressure was noticed at the left coronary bifurcation regions with wide angled models. Flow pattern was also changed with angled becoming wide in the simulated models. Our analysis shows direction relationship between coronary angulation and development of atherosclerosis. Future studies are required to perform computational fluid dynamic analysis in coronary models from patients' data with different degree of coronary stenosis.

Item Type: Book Section
Keywords: 3D left coronary artery models atherosclerosis development computational fluid dynamic analysis coronary stenosis flow simulation flow velocity analysis hemodynamics left coronary bifurcation angulations variable angulation effect wall pressure wall shear stress
Faculty / Department: Faculty of Science > Mathematics and Computer Science
Depositing User: Thanapong Chaichana
Date Deposited: 02 Aug 2017 10:09
Last Modified: 02 Aug 2017 10:09
URI: http://hira.hope.ac.uk/id/eprint/1501

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